About Glutathione S-transferase A2
Glutathione S-transferase A2 (GSTA2) is a protein
from Homo sapiens identified by UniProt accession
P09210, 222 residues long.
MolForge cross-references it against 0 known binders and
80 disease associations.
Target properties
| Protein name | Glutathione S-transferase A2 |
| UniProt accession | P09210 |
| Gene | GSTA2 |
| Organism | Homo sapiens |
| Length | 222 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | UNCLASSIFIED |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (80)
Diseases linked to this target (Open Targets).
- triglyceride measurement · score 0.47
- glomerular filtration rate · score 0.39
- mean corpuscular hemoglobin · score 0.37
- protein measurement · score 0.37
- mean corpuscular volume · score 0.35
- Red cell distribution width · score 0.35
- sex hormone-binding globulin measurement · score 0.35
- alcohol drinking · score 0.35
- alcohol consumption measurement · score 0.34
- serum urea measurement · score 0.32
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
| AF-P09210-F1 | alphafold | PREDICTED | 97.66 | — |
Amino-acid sequence (222 residues)
MAEKPKLHYS NIRGRMESIR WLLAAAGVEF EEKFIKSAED LDKLRNDGYL MFQQVPMVEI DGMKLVQTRA ILNYIASKYN LYGKDIKEKA LIDMYIEGIA DLGEMILLLP FSQPEEQDAK LALIQEKTKN RYFPAFEKVL KSHGQDYLVG NKLSRADIHL VELLYYVEEL DSSLISSFPL LKALKTRISN LPTVKKFLQP GSPRKPPMDE KSLEESRKIF RF
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