Glutathione S-transferase A2 (GSTA2)

Homo sapiens — UniProt P09210

Gene: GSTA2Homo sapiensSwissProt reviewed

About Glutathione S-transferase A2

Glutathione S-transferase A2 (GSTA2) is a protein from Homo sapiens identified by UniProt accession P09210, 222 residues long. MolForge cross-references it against 0 known binders and 80 disease associations.

Target properties

Protein nameGlutathione S-transferase A2
UniProt accessionP09210
GeneGSTA2
OrganismHomo sapiens
Length222 residues
Molecular weight—
EC numbers—
Target classUNCLASSIFIED
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (80)

Diseases linked to this target (Open Targets).

  • triglyceride measurement · score 0.47
  • glomerular filtration rate · score 0.39
  • mean corpuscular hemoglobin · score 0.37
  • protein measurement · score 0.37
  • mean corpuscular volume · score 0.35
  • Red cell distribution width · score 0.35
  • sex hormone-binding globulin measurement · score 0.35
  • alcohol drinking · score 0.35
  • alcohol consumption measurement · score 0.34
  • serum urea measurement · score 0.32

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-P09210-F1alphafoldPREDICTED97.66—

Amino-acid sequence (222 residues)

MAEKPKLHYS NIRGRMESIR WLLAAAGVEF EEKFIKSAED LDKLRNDGYL MFQQVPMVEI DGMKLVQTRA ILNYIASKYN LYGKDIKEKA LIDMYIEGIA DLGEMILLLP FSQPEEQDAK LALIQEKTKN RYFPAFEKVL KSHGQDYLVG NKLSRADIHL VELLYYVEEL DSSLISSFPL LKALKTRISN LPTVKKFLQP GSPRKPPMDE KSLEESRKIF RF

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Quick facts

UniProtP09210
GeneGSTA2
OrganismHomo sapiens
Length222
Binders0
Diseases80
View on UniProt