Growth-regulated alpha protein (CXCL1)

About Growth-regulated alpha protein

Growth-regulated alpha protein (CXCL1) is a protein from Homo sapiens identified by UniProt accession P09341, 107 residues long. MolForge cross-references it against 0 known binders and 834 disease associations.

Target properties

Protein name	Growth-regulated alpha protein
UniProt accession	P09341
Gene	CXCL1
Organism	Homo sapiens
Length	107 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (834)

Diseases linked to this target (Open Targets).

blood protein measurement · score 0.38
chemokine (C-X-C motif) ligand 1 measurement · score 0.35
growth-regulated alpha protein measurement · score 0.33
glioblastoma multiforme · score 0.28
CXCL1 measurement · score 0.22
neutrophil count · score 0.22
leukocyte count · score 0.21
head and neck squamous cell carcinoma · score 0.18
myeloid white cell count · score 0.17
neoplasm · score 0.12

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P09341-F1	alphafold	PREDICTED	80.81	—

Amino-acid sequence (107 residues)

MARAALSAAP SNPRLLRVAL LLLLLVAAGR RAAGASVATE LRCQCLQTLQ GIHPKNIQSV NVKSPGPHCA QTEVIATLKN GRKACLNPAS PIVKKIIEKM LNSDKSN

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards