Galectin-1 (LGALS1)

About Galectin-1

Galectin-1 (LGALS1) is a protein from Homo sapiens identified by UniProt accession P09382, 135 residues long. MolForge cross-references it against 0 known binders and 587 disease associations.

Target properties

Protein name	Galectin-1
UniProt accession	P09382
Gene	LGALS1
Organism	Homo sapiens
Length	135 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (587)

Diseases linked to this target (Open Targets).

leukocyte count · score 0.14
myeloid white cell count · score 0.13
neoplasm · score 0.12
hepatocellular carcinoma · score 0.12
gonorrhea · score 0.11
glioblastoma multiforme · score 0.11
inflammatory bowel disease · score 0.10
type 2 diabetes mellitus · score 0.10
cancer · score 0.10
acute lymphoblastic leukemia · score 0.10

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P09382-F1	alphafold	PREDICTED	96.48	—

Amino-acid sequence (135 residues)

MACGLVASNL NLKPGECLRV RGEVAPDAKS FVLNLGKDSN NLCLHFNPRF NAHGDANTIV CNSKDGGAWG TEQREAVFPF QPGSVAEVCI TFDQANLTVK LPDGYEFKFP NRLNLEAINY MAADGDFKIK CVAFD

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards