Dihydropteridine reductase (QDPR)

About Dihydropteridine reductase

Dihydropteridine reductase (QDPR) is a protein from Homo sapiens identified by UniProt accession P09417, 244 residues long. MolForge cross-references it against 0 known binders and 124 disease associations.

Target properties

Protein name	Dihydropteridine reductase
UniProt accession	P09417
Gene	QDPR
Organism	Homo sapiens
Length	244 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P09417-F1	alphafold	PREDICTED	96.10	—

Amino-acid sequence (244 residues)

MAAAAAAGEA RRVLVYGGRG ALGSRCVQAF RARNWWVASV DVVENEEASA SIIVKMTDSF TEQADQVTAE VGKLLGEEKV DAILCVAGGW AGGNAKSKSL FKNCDLMWKQ SIWTSTISSH LATKHLKEGG LLTLAGAKAA LDGTPGMIGY GMAKGAVHQL CQSLAGKNSG MPPGAAAIAV LPVTLDTPMN RKSMPEADFS SWTPLEFLVE TFHDWITGKN RPSSGSLIQV VTTEGRTELT PAYF

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards