About Glutathione S-transferase Mu 1
Glutathione S-transferase Mu 1 (GSTM1) is a protein
from Homo sapiens identified by UniProt accession
P09488, 218 residues long.
MolForge cross-references it against 0 known binders and
1,589 disease associations.
Target properties
| Protein name | Glutathione S-transferase Mu 1 |
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| UniProt accession | P09488 |
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| Gene | GSTM1 |
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| Organism | Homo sapiens |
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| Length | 218 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
|---|
| Pocket score | — |
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| Max clinical phase | — |
|---|
Disease associations (1589)
Diseases linked to this target (Open Targets).
- mean platelet volume · score 0.30
- sex hormone-binding globulin measurement · score 0.28
- platelet count · score 0.23
- testosterone measurement · score 0.20
- apolipoprotein B measurement · score 0.19
- apolipoprotein A 1 measurement · score 0.19
- monocyte count · score 0.17
- platelet crit · score 0.17
- serum alanine aminotransferase measurement · score 0.16
- bilirubin measurement · score 0.15
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P09488-F1 | alphafold | PREDICTED | 98.27 | — |
Amino-acid sequence (218 residues)
MPMILGYWDI RGLAHAIRLL LEYTDSSYEE KKYTMGDAPD YDRSQWLNEK FKLGLDFPNL PYLIDGAHKI TQSNAILCYI ARKHNLCGET EEEKIRVDIL ENQTMDNHMQ LGMICYNPEF EKLKPKYLEE LPEKLKLYSE FLGKRPWFAG NKITFVDFLV YDVLDLHRIF EPKCLDAFPN LKDFISRFEG LEKISAYMKS SRFLPRPVFS KMAVWGNK
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