About Clathrin light chain B
Clathrin light chain B (CLTB) is a protein
from Homo sapiens identified by UniProt accession
P09497, 229 residues long.
MolForge cross-references it against 0 known binders and
26 disease associations.
Target properties
| Protein name | Clathrin light chain B |
|---|
| UniProt accession | P09497 |
|---|
| Gene | CLTB |
|---|
| Organism | Homo sapiens |
|---|
| Length | 229 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (26)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.26
- serum albumin measurement · score 0.24
- body height · score 0.17
- Red cell distribution width · score 0.05
- colorectal cancer · score 0.02
- hepatocellular carcinoma · score 0.01
- monoclonal gammopathy · score 0.01
- non-small cell lung carcinoma · score 0.01
- calf circumference measurement · score 0.00
- neoplasm · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P09497-F1 | alphafold | PREDICTED | 72.37 | — |
Amino-acid sequence (229 residues)
MADDFGFFSS SESGAPEAAE EDPAAAFLAQ QESEIAGIEN DEGFGAPAGS HAAPAQPGPT SGAGSEDMGT TVNGDVFQEA NGPADGYAAI AQADRLTQEP ESIRKWREEQ RKRLQELDAA SKVTEQEWRE KAKKDLEEWN QRQSEQVEKN KINNRIADKA FYQQPDADII GYVASEEAFV KESKEETPGT EWEKVAQLCD FNPKSSKQCK DVSRLRSVLM SLKQTPLSR
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