About Annexin A4
Annexin A4 (ANXA4) is a protein
from Homo sapiens identified by UniProt accession
P09525, 319 residues long.
MolForge cross-references it against 0 known binders and
143 disease associations.
Target properties
| Protein name | Annexin A4 |
|---|
| UniProt accession | P09525 |
|---|
| Gene | ANXA4 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 319 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (143)
Diseases linked to this target (Open Targets).
- atrial fibrillation · score 0.29
- neurodegenerative disease · score 0.27
- C-reactive protein measurement · score 0.23
- hemoglobin measurement · score 0.18
- Red cell distribution width · score 0.18
- reticulocyte count · score 0.16
- urate measurement · score 0.15
- hematocrit · score 0.14
- erythrocyte count · score 0.13
- chronotype measurement · score 0.12
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P09525-F1 | alphafold | PREDICTED | 96.70 | — |
Amino-acid sequence (319 residues)
MATKGGTVKA ASGFNAMEDA QTLRKAMKGL GTDEDAIISV LAYRNTAQRQ EIRTAYKSTI GRDLIDDLKS ELSGNFEQVI VGMMTPTVLY DVQELRRAMK GAGTDEGCLI EILASRTPEE IRRISQTYQQ QYGRSLEDDI RSDTSFMFQR VLVSLSAGGR DEGNYLDDAL VRQDAQDLYE AGEKKWGTDE VKFLTVLCSR NRNHLLHVFD EYKRISQKDI EQSIKSETSG SFEDALLAIV KCMRNKSAYF AEKLYKSMKG LGTDDNTLIR VMVSRAEIDM LDIRAHFKRL YGKSLYSFIK GDTSGDYRKV LLVLCGGDD
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