Inhibin beta B chain (INHBB)

About Inhibin beta B chain

Inhibin beta B chain (INHBB) is a protein from Homo sapiens identified by UniProt accession P09529, 407 residues long. MolForge cross-references it against 0 known binders and 182 disease associations.

Target properties

Protein name	Inhibin beta B chain
UniProt accession	P09529
Gene	INHBB
Organism	Homo sapiens
Length	407 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Approved drugs hitting this target (1)

DrugCentral-linked approved drugs that act on this protein.

Disease associations (182)

Diseases linked to this target (Open Targets).

prostate carcinoma · score 0.39
breast carcinoma · score 0.39
breast size · score 0.32
puberty onset measurement · score 0.27
age at menopause · score 0.26
urate measurement · score 0.26
low density lipoprotein cholesterol measurement · score 0.25
testicular hydrocele · score 0.24
hair colour measurement · score 0.24
protein measurement · score 0.24

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P09529-F1	alphafold	PREDICTED	73.79	—

Amino-acid sequence (407 residues)

MDGLPGRALG AACLLLLAAG WLGPEAWGSP TPPPTPAAPP PPPPPGSPGG SQDTCTSCGG FRRPEELGRV DGDFLEAVKR HILSRLQMRG RPNITHAVPK AAMVTALRKL HAGKVREDGR VEIPHLDGHA SPGADGQERV SEIISFAETD GLASSRVRLY FFISNEGNQN LFVVQASLWL YLKLLPYVLE KGSRRKVRVK VYFQEQGHGD RWNMVEKRVD LKRSGWHTFP LTEAIQALFE RGERRLNLDV QCDSCQELAV VPVFVDPGEE SHRPFVVVQA RLGDSRHRIR KRGLECDGRT NLCCRQQFFI DFRLIGWNDW IIAPTGYYGN YCEGSCPAYL AGVPGSASSF HTAVVNQYRM RGLNPGTVNS CCIPTKLSTM SMLYFDDEYN IVKRDVPNMI VEECGCA

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards