About T-cell antigen CD7
T-cell antigen CD7 (CD7) is a protein
from Homo sapiens identified by UniProt accession
P09564, 240 residues long.
MolForge cross-references it against 0 known binders and
325 disease associations.
Target properties
| Protein name | T-cell antigen CD7 |
| UniProt accession | P09564 |
| Gene | CD7 |
| Organism | Homo sapiens |
| Length | 240 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | UNCLASSIFIED |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (325)
Diseases linked to this target (Open Targets).
- acute myeloid leukemia · score 0.11
- acute lymphoblastic leukemia · score 0.10
- neoplasm · score 0.10
- early-onset non-syndromic cataract · score 0.10
- chronic myelogenous leukemia · score 0.08
- isolated ectopia lentis · score 0.08
- hereditary hyperferritinemia with congenital cataracts · score 0.08
- Total congenital cataract · score 0.08
- Posterior polar cataract · score 0.08
- Cataract-microcornea syndrome · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
| AF-P09564-F1 | alphafold | PREDICTED | 76.98 | — |
Amino-acid sequence (240 residues)
MAGPPRLLLL PLLLALARGL PGALAAQEVQ QSPHCTTVPV GASVNITCST SGGLRGIYLR QLGPQPQDII YYEDGVVPTT DRRFRGRIDF SGSQDNLTIT MHRLQLSDTG TYTCQAITEV NVYGSGTLVL VTEEQSQGWH RCSDAPPRAS ALPAPPTGSA LPDPQTASAL PDPPAASALP AALAVISFLL GLGLGVACVL ARTQIKKLCS WRDKNSAACV VYEDMSHSRC NTLSSPNQYQ
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