T-cell antigen CD7 (CD7)

Homo sapiens — UniProt P09564

Gene: CD7Homo sapiensSwissProt reviewed

About T-cell antigen CD7

T-cell antigen CD7 (CD7) is a protein from Homo sapiens identified by UniProt accession P09564, 240 residues long. MolForge cross-references it against 0 known binders and 325 disease associations.

Target properties

Protein nameT-cell antigen CD7
UniProt accessionP09564
GeneCD7
OrganismHomo sapiens
Length240 residues
Molecular weight—
EC numbers—
Target classUNCLASSIFIED
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (325)

Diseases linked to this target (Open Targets).

  • acute myeloid leukemia · score 0.11
  • acute lymphoblastic leukemia · score 0.10
  • neoplasm · score 0.10
  • early-onset non-syndromic cataract · score 0.10
  • chronic myelogenous leukemia · score 0.08
  • isolated ectopia lentis · score 0.08
  • hereditary hyperferritinemia with congenital cataracts · score 0.08
  • Total congenital cataract · score 0.08
  • Posterior polar cataract · score 0.08
  • Cataract-microcornea syndrome · score 0.07

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-P09564-F1alphafoldPREDICTED76.98—

Amino-acid sequence (240 residues)

MAGPPRLLLL PLLLALARGL PGALAAQEVQ QSPHCTTVPV GASVNITCST SGGLRGIYLR QLGPQPQDII YYEDGVVPTT DRRFRGRIDF SGSQDNLTIT MHRLQLSDTG TYTCQAITEV NVYGSGTLVL VTEEQSQGWH RCSDAPPRAS ALPAPPTGSA LPDPQTASAL PDPPAASALP AALAVISFLL GLGLGVACVL ARTQIKKLCS WRDKNSAACV VYEDMSHSRC NTLSSPNQYQ

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Quick facts

UniProtP09564
GeneCD7
OrganismHomo sapiens
Length240
Binders0
Diseases325
View on UniProt