About Homeobox protein Hox-B7
Homeobox protein Hox-B7 (HOXB7) is a protein
from Homo sapiens identified by UniProt accession
P09629, 217 residues long.
MolForge cross-references it against 0 known binders and
174 disease associations.
Target properties
| Protein name | Homeobox protein Hox-B7 |
|---|
| UniProt accession | P09629 |
|---|
| Gene | HOXB7 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 217 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (174)
Diseases linked to this target (Open Targets).
- low density lipoprotein cholesterol measurement · score 0.28
- systolic blood pressure · score 0.21
- hypertension · score 0.16
- hip bone mineral density · score 0.15
- mean arterial pressure · score 0.15
- diastolic blood pressure · score 0.14
- bilirubin measurement · score 0.13
- HbA1c measurement · score 0.12
- total cholesterol measurement · score 0.12
- neoplasm · score 0.11
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P09629-F1 | alphafold | PREDICTED | 63.92 | — |
Amino-acid sequence (217 residues)
MSSLYYANTL FSKYPASSSV FATGAFPEQT SCAFASNPQR PGYGAGSGAS FAASMQGLYP GGGGMAGQSA AGVYAAGYGL EPSSFNMHCA PFEQNLSGVC PGDSAKAAGA KEQRDSDLAA ESNFRIYPWM RSSGTDRKRG RQTYTRYQTL ELEKEFHYNR YLTRRRRIEI AHTLCLTERQ IKIWFQNRRM KWKKENKTAG PGTTGQDRAE AEEEEEE
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