About Homeobox protein Hox-C6
Homeobox protein Hox-C6 (HOXC6) is a protein
from Homo sapiens identified by UniProt accession
P09630, 235 residues long.
MolForge cross-references it against 0 known binders and
171 disease associations.
Target properties
| Protein name | Homeobox protein Hox-C6 |
|---|
| UniProt accession | P09630 |
|---|
| Gene | HOXC6 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 235 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (171)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.54
- heel bone mineral density · score 0.29
- BMI-adjusted waist-hip ratio · score 0.28
- BMI-adjusted waist circumference · score 0.28
- appendicular lean mass · score 0.24
- waist-hip ratio · score 0.21
- bone quantitative ultrasound measurement · score 0.20
- spine bone size · score 0.20
- vital capacity · score 0.20
- alcohol drinking · score 0.17
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P09630-F1 | alphafold | PREDICTED | 63.17 | — |
Amino-acid sequence (235 residues)
MNSYFTNPSL SCHLAGGQDV LPNVALNSTA YDPVRHFSTY GAAVAQNRIY STPFYSPQEN VVFSSSRGPY DYGSNSFYQE KDMLSNCRQN TLGHNTQTSI AQDFSSEQGR TAPQDQKASI QIYPWMQRMN SHSGVGYGAD RRRGRQIYSR YQTLELEKEF HFNRYLTRRR RIEIANALCL TERQIKIWFQ NRRMKWKKES NLTSTLSGGG GGATADSLGG KEEKREETEE EKQKE
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