Cytochrome c oxidase subunit 6C (COX6C)

About Cytochrome c oxidase subunit 6C

Cytochrome c oxidase subunit 6C (COX6C) is a protein from Homo sapiens identified by UniProt accession P09669, 75 residues long. MolForge cross-references it against 0 known binders and 105 disease associations.

Target properties

Protein name	Cytochrome c oxidase subunit 6C
UniProt accession	P09669
Gene	COX6C
Organism	Homo sapiens
Length	75 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (105)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.55
squamous cell lung carcinoma · score 0.23
breast adenocarcinoma · score 0.23
small cell lung carcinoma · score 0.21
lung adenocarcinoma · score 0.20
skin carcinoma · score 0.19
breast carcinoma · score 0.19
esophageal squamous cell carcinoma · score 0.19
acute myeloid leukemia · score 0.19
chronic lymphocytic leukemia · score 0.18

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P09669-F1	alphafold	PREDICTED	94.80	—

Amino-acid sequence (75 residues)

MAPEVLPKPR MRGLLARRLR NHMAVAFVLS LGVAALYKFR VADQRKKAYA DFYRNYDVMK DFEEMRKAGI FQSVK

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards