Gastric inhibitory polypeptide (GIP)

About Gastric inhibitory polypeptide

Gastric inhibitory polypeptide (GIP) is a protein from Homo sapiens identified by UniProt accession P09681, 153 residues long. MolForge cross-references it against 0 known binders and 202 disease associations.

Target properties

Protein name	Gastric inhibitory polypeptide
UniProt accession	P09681
Gene	GIP
Organism	Homo sapiens
Length	153 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (202)

Diseases linked to this target (Open Targets).

type 2 diabetes mellitus · score 0.27
appendicular lean mass · score 0.26
body height · score 0.23
neurodegenerative disease · score 0.23
systolic blood pressure · score 0.21
sitting height measurement · score 0.21
coronary artery disease · score 0.19
vital capacity · score 0.18
myocardial infarction · score 0.17
eosinophil count · score 0.17

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P09681-F1	alphafold	PREDICTED	69.21	—

Amino-acid sequence (153 residues)

MVATKTFALL LLSLFLAVGL GEKKEGHFSA LPSLPVGSHA KVSSPQPRGP RYAEGTFISD YSIAMDKIHQ QDFVNWLLAQ KGKKNDWKHN ITQREARALE LASQANRKEE EAVEPQSSPA KNPSDEDLLR DLLIQELLAC LLDQTNLCRL RSR

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards