Secretin (SCT)

About Secretin

Secretin (SCT) is a protein from Homo sapiens identified by UniProt accession P09683, 121 residues long. MolForge cross-references it against 0 known binders and 197 disease associations.

Target properties

Protein name	Secretin
UniProt accession	P09683
Gene	SCT
Organism	Homo sapiens
Length	121 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (197)

Diseases linked to this target (Open Targets).

systemic lupus erythematosus · score 0.05
cystic fibrosis · score 0.04
myositis · score 0.04
systemic scleroderma · score 0.04
rheumatoid arthritis · score 0.04
primary biliary cirrhosis · score 0.04
Hyperglycemia · score 0.04
Autism · score 0.03
Zollinger-Ellison Syndrome · score 0.03
alcoholic liver cirrhosis · score 0.03

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P09683-F1	alphafold	PREDICTED	65.85	—

Amino-acid sequence (121 residues)

MAPRPLLLLL LLLGGSAARP APPRARRHSD GTFTSELSRL REGARLQRLL QGLVGKRSEQ DAENSMAWTR LSAGLLCPSG SNMPILQAWM PLDGTWSPWL PPGPMVSEPA GAAAEGTLRP R

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards