T-cell surface glycoprotein CD3 gamma chain (CD3G)

About T-cell surface glycoprotein CD3 gamma chain

T-cell surface glycoprotein CD3 gamma chain (CD3G) is a protein from Homo sapiens identified by UniProt accession P09693, 182 residues long. MolForge cross-references it against 0 known binders and 178 disease associations.

Target properties

Protein name	T-cell surface glycoprotein CD3 gamma chain
UniProt accession	P09693
Gene	CD3G
Organism	Homo sapiens
Length	182 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P09693-F1	alphafold	PREDICTED	75.27	—

Amino-acid sequence (182 residues)

MEQGKGLAVL ILAIILLQGT LAQSIKGNHL VKVYDYQEDG SVLLTCDAEA KNITWFKDGK MIGFLTEDKK KWNLGSNAKD PRGMYQCKGS QNKSKPLQVY YRMCQNCIEL NAATISGFLF AEIVSIFVLA VGVYFIAGQD GVRQSRASDK QTLLPNDQLY QPLKDREDDQ YSHLQGNQLR RN

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards