Interferon alpha-inducible protein 6 (IFI6)

About Interferon alpha-inducible protein 6

Interferon alpha-inducible protein 6 (IFI6) is a protein from Homo sapiens identified by UniProt accession P09912, 130 residues long. MolForge cross-references it against 0 known binders and 119 disease associations.

Target properties

Protein name	Interferon alpha-inducible protein 6
UniProt accession	P09912
Gene	IFI6
Organism	Homo sapiens
Length	130 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (119)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.23
esophageal squamous cell carcinoma · score 0.09
systolic blood pressure · score 0.09
melanoma · score 0.08
neoplasm · score 0.06
hepatitis C virus infection · score 0.05
body weight · score 0.05
esophageal adenocarcinoma · score 0.04
infection · score 0.03
infect · score 0.03

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P09912-F1	alphafold	PREDICTED	54.15	—

Amino-acid sequence (130 residues)

MRQKAVSLFL CYLLLFTCSG VEAGKKKCSE SSDSGSGFWK ALTFMAVGGG LAVAGLPALG FTGAGIAANS VAASLMSWSA ILNGGGVPAG GLVATLQSLG AGGSSVVIGN IGALMGYATH KYLDSEEDEE

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards