About Interferon-induced protein with tetratricopeptide repeats 2
Interferon-induced protein with tetratricopeptide repeats 2 (IFIT2) is a protein
from Homo sapiens identified by UniProt accession
P09913, 472 residues long.
MolForge cross-references it against 0 known binders and
249 disease associations.
Target properties
| Protein name | Interferon-induced protein with tetratricopeptide repeats 2 |
|---|
| UniProt accession | P09913 |
|---|
| Gene | IFIT2 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 472 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (249)
Diseases linked to this target (Open Targets).
- blood protein measurement · score 0.27
- alkaline phosphatase measurement · score 0.26
- coronary artery disease · score 0.12
- myocardial infarction · score 0.11
- C-reactive protein measurement · score 0.10
- leukocyte count · score 0.10
- serum alanine aminotransferase measurement · score 0.10
- neutrophil count · score 0.10
- Red cell distribution width · score 0.09
- myeloid white cell count · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P09913-F1 | alphafold | PREDICTED | 88.64 | — |
Amino-acid sequence (472 residues)
MSENNKNSLE SSLRQLKCHF TWNLMEGENS LDDFEDKVFY RTEFQNREFK ATMCNLLAYL KHLKGQNEAA LECLRKAEEL IQQEHADQAE IRSLVTWGNY AWVYYHMGRL SDVQIYVDKV KHVCEKFSSP YRIESPELDC EEGWTRLKCG GNQNERAKVC FEKALEKKPK NPEFTSGLAI ASYRLDNWPP SQNAIDPLRQ AIRLNPDNQY LKVLLALKLH KMREEGEEEG EGEKLVEEAL EKAPGVTDVL RSAAKFYRRK DEPDKAIELL KKALEYIPNN AYLHCQIGCC YRAKVFQVMN LRENGMYGKR KLLELIGHAV AHLKKADEAN DNLFRVCSIL ASLHALADQY EDAEYYFQKE FSKELTPVAK QLLHLRYGNF QLYQMKCEDK AIHHFIEGVK INQKSREKEK MKDKLQKIAK MRLSKNGADS EALHVLAFLQ ELNEKMQQAD EDSERGLESG SLIPSASSWN GE
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