About Granulocyte colony-stimulating factor
Granulocyte colony-stimulating factor (CSF3) is a protein
from Homo sapiens identified by UniProt accession
P09919, 207 residues long.
MolForge cross-references it against 0 known binders and
1,341 disease associations.
Target properties
| Protein name | Granulocyte colony-stimulating factor |
|---|
| UniProt accession | P09919 |
|---|
| Gene | CSF3 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 207 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (1341)
Diseases linked to this target (Open Targets).
- neutrophil count · score 0.35
- neutrophil percentage of leukocytes · score 0.34
- lymphocyte percentage of leukocytes · score 0.33
- myeloid white cell count · score 0.32
- granulocyte count · score 0.31
- leukocyte count · score 0.31
- sum of neutrophil and eosinophil counts · score 0.29
- sum of basophil and neutrophil counts · score 0.29
- basophil count · score 0.24
- monocyte percentage of leukocytes · score 0.24
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P09919-F1 | alphafold | PREDICTED | 84.23 | — |
Amino-acid sequence (207 residues)
MAGPATQSPM KLMALQLLLW HSALWTVQEA TPLGPASSLP QSFLLKCLEQ VRKIQGDGAA LQEKLVSECA TYKLCHPEEL VLLGHSLGIP WAPLSSCPSQ ALQLAGCLSQ LHSGLFLYQG LLQALEGISP ELGPTLDTLQ LDVADFATTI WQQMEELGMA PALQPTQGAM PAFASAFQRR AGGVLVASHL QSFLEVSYRV LRHLAQP
Explore Granulocyte colony-stimulating factor with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets