About Peroxisomal coenzyme A diphosphatase NUDT7
Peroxisomal coenzyme A diphosphatase NUDT7 (NUDT7) is a protein
from Homo sapiens identified by UniProt accession
P0C024, 238 residues long.
MolForge cross-references it against 0 known binders and
55 disease associations.
Target properties
| Protein name | Peroxisomal coenzyme A diphosphatase NUDT7 |
| UniProt accession | P0C024 |
| Gene | NUDT7 |
| Organism | Homo sapiens |
| Length | 238 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | UNCLASSIFIED |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (55)
Diseases linked to this target (Open Targets).
- Rectal prolapse · score 0.29
- brain volume measurement · score 0.27
- open-angle glaucoma · score 0.24
- intraocular pressure measurement · score 0.19
- low grade glioma · score 0.18
- vital capacity · score 0.17
- refractive error measurement · score 0.10
- balding measurement · score 0.08
- osteoarthritis · score 0.07
- glaucoma · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
| AF-P0C024-F1 | alphafold | PREDICTED | 94.23 | — |
Amino-acid sequence (238 residues)
MSRLGLPEEP VRNSLLDDAK ARLRKYDIGG KYSHLPYNKY SVLLPLVAKE GKLHLLFTVR SEKLRRAPGE VCFPGGKRDP TDMDDAATAL REAQEEVGLR PHQVEVVCCL VPCLIDTDTL ITPFVGLIDH NFQAQPNPAE VKDVFLVPLA YFLHPQVHDQ HYVTRLGHRF INHIFEYTNP EDGVTYQIKG MTANLAVLVA FIILEKKPTF EVQFNLNDVL ASSEELFLKV HKKATSRL
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