Peroxisomal coenzyme A diphosphatase NUDT7 (NUDT7)

Homo sapiens — UniProt P0C024

Gene: NUDT7Homo sapiensSwissProt reviewed

About Peroxisomal coenzyme A diphosphatase NUDT7

Peroxisomal coenzyme A diphosphatase NUDT7 (NUDT7) is a protein from Homo sapiens identified by UniProt accession P0C024, 238 residues long. MolForge cross-references it against 0 known binders and 55 disease associations.

Target properties

Protein namePeroxisomal coenzyme A diphosphatase NUDT7
UniProt accessionP0C024
GeneNUDT7
OrganismHomo sapiens
Length238 residues
Molecular weight—
EC numbers—
Target classUNCLASSIFIED
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (55)

Diseases linked to this target (Open Targets).

  • Rectal prolapse · score 0.29
  • brain volume measurement · score 0.27
  • open-angle glaucoma · score 0.24
  • intraocular pressure measurement · score 0.19
  • low grade glioma · score 0.18
  • vital capacity · score 0.17
  • refractive error measurement · score 0.10
  • balding measurement · score 0.08
  • osteoarthritis · score 0.07
  • glaucoma · score 0.07

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-P0C024-F1alphafoldPREDICTED94.23—

Amino-acid sequence (238 residues)

MSRLGLPEEP VRNSLLDDAK ARLRKYDIGG KYSHLPYNKY SVLLPLVAKE GKLHLLFTVR SEKLRRAPGE VCFPGGKRDP TDMDDAATAL REAQEEVGLR PHQVEVVCCL VPCLIDTDTL ITPFVGLIDH NFQAQPNPAE VKDVFLVPLA YFLHPQVHDQ HYVTRLGHRF INHIFEYTNP EDGVTYQIKG MTANLAVLVA FIILEKKPTF EVQFNLNDVL ASSEELFLKV HKKATSRL

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Quick facts

UniProtP0C024
GeneNUDT7
OrganismHomo sapiens
Length238
Binders0
Diseases55
View on UniProt