About m7GpppN-mRNA hydrolase NUDT17
m7GpppN-mRNA hydrolase NUDT17 (NUDT17) is a protein
from Homo sapiens identified by UniProt accession
P0C025, 328 residues long.
MolForge cross-references it against 0 known binders and
14 disease associations.
Target properties
| Protein name | m7GpppN-mRNA hydrolase NUDT17 |
|---|
| UniProt accession | P0C025 |
|---|
| Gene | NUDT17 |
|---|
| Organism | Homo sapiens |
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| Length | 328 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
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| Max clinical phase | — |
|---|
Disease associations (14)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.22
- breast carcinoma · score 0.14
- mathematical ability · score 0.14
- uric acid measurement · score 0.10
- urate measurement · score 0.10
- platelet count · score 0.04
- diastolic blood pressure · score 0.03
- osteosarcoma · score 0.03
- breast cancer · score 0.02
- neoplasm · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P0C025-F1 | alphafold | PREDICTED | 85.15 | — |
Amino-acid sequence (328 residues)
MAEVRVQLLL SRRPESVSFA RSVCGLLGAG PGLGTWPIHC SLKRGRLVLS SRPFPGASAR LPLQRPPFCP FAALEERPRV PGAELPTDRG VDLGVAVILQ SSDKTVLLTR RARTLSVSPN LWVPPGGHVE LEEELLDGGL RELWEESGLH LPQGQFSWVP LGLWESAYPP RLSWGLPKYH HIVLYLLVIS QESQQQLQAR IQPNPNEVSA LMWLTPDVAA AVAAAEDGTE TPGLLPQDLP PSVLAVELEE DGRARPLVLH MSTLLRMIPT MAEDKERVST GTKFALKLWL QHLGRTPPPC KSAAYLDPGP AKEEWNMDPL PPNQGSGK
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