Neuropeptide S (NPS)

About Neuropeptide S

Neuropeptide S (NPS) is a protein from Homo sapiens identified by UniProt accession P0C0P6, 89 residues long. MolForge cross-references it against 0 known binders and 292 disease associations.

Target properties

Protein name	Neuropeptide S
UniProt accession	P0C0P6
Gene	NPS
Organism	Homo sapiens
Length	89 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (292)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.31
chronotype measurement · score 0.23
neurofibrillary tangles measurement · score 0.18
PHF-tau measurement · score 0.18
metabolite measurement · score 0.13
bladder disease · score 0.10
protein measurement · score 0.08
major depressive disorder · score 0.06
Spinal cord injury · score 0.06
longitudinal BMI measurement · score 0.04

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P0C0P6-F1	alphafold	PREDICTED	65.31	—

Amino-acid sequence (89 residues)

MISSVKLNLI LVLSLSTMHV FWCYPVPSSK VSGKSDYFLI LLNSCPTRLD RSKELAFLKP ILEKMFVKRS FRNGVGTGMK KTSFQRAKS

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards