About TCF3 fusion partner
TCF3 fusion partner (TFPT) is a protein
from Homo sapiens identified by UniProt accession
P0C1Z6, 253 residues long.
MolForge cross-references it against 0 known binders and
103 disease associations.
Target properties
| Protein name | TCF3 fusion partner |
|---|
| UniProt accession | P0C1Z6 |
|---|
| Gene | TFPT |
|---|
| Organism | Homo sapiens |
|---|
| Length | 253 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (103)
Diseases linked to this target (Open Targets).
- low grade glioma · score 0.23
- breast adenocarcinoma · score 0.23
- hepatocellular carcinoma · score 0.19
- colon adenocarcinoma · score 0.19
- acute myeloid leukemia · score 0.18
- head and neck squamous cell carcinoma · score 0.18
- colorectal adenocarcinoma · score 0.18
- clear cell renal carcinoma · score 0.18
- gastric carcinoma · score 0.18
- breast carcinoma · score 0.18
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P0C1Z6-F1 | alphafold | PREDICTED | 65.96 | — |
Amino-acid sequence (253 residues)
MELEQREGTM AAVGFEEFSA PPGSELALPP LFGGHILESE LETEVEFVSG GLGGSGLRER DEEEEAARGR RRRQRELNRR KYQALGRRCR EIEQVNERVL NRLHQVQRIT RRLQQERRFL MRVLDSYGDD YRASQFTIVL EDEGSQGTDA PTPGNAENEP PEKETLSPPR RTPAPPEPGS PAPGEGPSGR KRRRVPRDGR RAGNALTPEL APVQIKVEED FGFEADEALD SSWVSRGPDK LLPYPTLASP ASD
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