About Coiled-coil domain-containing protein 175
Coiled-coil domain-containing protein 175 (CCDC175) is a protein
from Homo sapiens identified by UniProt accession
P0C221, 793 residues long.
MolForge cross-references it against 0 known binders and
20 disease associations.
Target properties
| Protein name | Coiled-coil domain-containing protein 175 |
|---|
| UniProt accession | P0C221 |
|---|
| Gene | CCDC175 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 793 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (20)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.34
- monocyte count · score 0.20
- unipolar depression · score 0.11
- schizophrenia · score 0.09
- attention deficit hyperactivity disorder · score 0.09
- antisocial behaviour measurement · score 0.08
- substance abuse · score 0.08
- body height · score 0.05
- obsessive-compulsive disorder · score 0.03
- Tourette syndrome · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P0C221-F1 | alphafold | PREDICTED | 75.56 | — |
Amino-acid sequence (793 residues)
MALSPWTPGL GAGEKLVQAA AVSTGPSLEL CTLPSTLGSS VAVEALEQLF VVEQSLQSDY FKCNEEAKIF LKDIAVAVKK LEEMRKATID LLEIESMELN KLYYLLETLP NSIKRELEEC VRDARRLNLF EINTIKMRIT RTENEIELLK KKITDLTKYN EALGEKQEEL ARKHARFVLS LNQTMEKKAT TTVYINETYT KINLKREDIA LQKKCIQEAE ELMEKERAEY LIRKQELTAQ INEFENTREV KRMETYQKKK ELDKLQTKMS KIKETVTVSA AVLSDHNLEI ARLHESIRYW EQEVSELKKD LAILEAKLCF FTDNKEKLDD ISNDEKNEFL NKIKQLVETL HAARMEYKDL REKMKTLARQ YKIVLSEEEK AFLQKQKIHD ENQKQLTFIS QKEYFLSQKR VDIKNMEEGL ITLQELQQAT KTVYQQQIKI LSANLERESQ RCVITQWKMA CLRKKHARWT AKIKAEIQAI TEKIQNAEVR RIELLNETSF RQQEISGFVA QIEKLTTELK EEEKAFVNKE KMLMKELSKY EEIFVKETQI NKEKEEELVE YLPQLQVAEQ EYKEKRRKLE ELSNIITAQR QEEDLLNNHI FLFTRDFSRY ISNMEDVKQE LQQLRDQESK KNKDHFETLK NLENGFYIND QKADLLLLEN KKLKEYILYL KNNIEKYREG QEALMHTSSD LSRQLIAQEA QYKDLWAEFQ TTVKILVDNG EETLQDINNL TDKLRERDEK MQHVSTWLRG SLEGLRLLVE QESPMDLLKK KKHIRTRVHF PVVKCTEKNT LTK
Explore Coiled-coil domain-containing protein 175 with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets