About Protein FAM163B
Protein FAM163B (FAM163B) is a protein
from Homo sapiens identified by UniProt accession
P0C2L3, 166 residues long.
MolForge cross-references it against 0 known binders and
23 disease associations.
Target properties
| Protein name | Protein FAM163B |
| UniProt accession | P0C2L3 |
| Gene | FAM163B |
| Organism | Homo sapiens |
| Length | 166 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | UNCLASSIFIED |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (23)
Diseases linked to this target (Open Targets).
- smoking cessation · score 0.26
- smoking behavior · score 0.21
- cigarettes per day measurement · score 0.19
- smoking status measurement · score 0.18
- nicotine dependence · score 0.16
- time to first cigarette measurement · score 0.15
- tobacco smoke exposure measurement · score 0.14
- smoking behaviour measurement · score 0.13
- leukocyte count · score 0.12
- neutrophil count · score 0.12
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
| AF-P0C2L3-F1 | alphafold | PREDICTED | 57.59 | — |
Amino-acid sequence (166 residues)
MTAGTVVITG GILATVILLC IIAVLCYCRL QYYCCKKDES EEDEEEPDFA VHSHLPPLHS NRNLVLTNGP ALYPTASTSF SQKSPQARAL CRSCSHCEPP TFFLQEPPEE EEDVLNGGER VLYKSVSQED VELPPGGFGG LQALNPNRLS AMREAFARSR SISTDV
Explore Protein FAM163B with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets