Protein FAM163B (FAM163B)

Homo sapiens — UniProt P0C2L3

Gene: FAM163BHomo sapiensSwissProt reviewed

About Protein FAM163B

Protein FAM163B (FAM163B) is a protein from Homo sapiens identified by UniProt accession P0C2L3, 166 residues long. MolForge cross-references it against 0 known binders and 23 disease associations.

Target properties

Protein nameProtein FAM163B
UniProt accessionP0C2L3
GeneFAM163B
OrganismHomo sapiens
Length166 residues
Molecular weight—
EC numbers—
Target classUNCLASSIFIED
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (23)

Diseases linked to this target (Open Targets).

  • smoking cessation · score 0.26
  • smoking behavior · score 0.21
  • cigarettes per day measurement · score 0.19
  • smoking status measurement · score 0.18
  • nicotine dependence · score 0.16
  • time to first cigarette measurement · score 0.15
  • tobacco smoke exposure measurement · score 0.14
  • smoking behaviour measurement · score 0.13
  • leukocyte count · score 0.12
  • neutrophil count · score 0.12

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-P0C2L3-F1alphafoldPREDICTED57.59—

Amino-acid sequence (166 residues)

MTAGTVVITG GILATVILLC IIAVLCYCRL QYYCCKKDES EEDEEEPDFA VHSHLPPLHS NRNLVLTNGP ALYPTASTSF SQKSPQARAL CRSCSHCEPP TFFLQEPPEE EEDVLNGGER VLYKSVSQED VELPPGGFGG LQALNPNRLS AMREAFARSR SISTDV

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Quick facts

UniProtP0C2L3
GeneFAM163B
OrganismHomo sapiens
Length166
Binders0
Diseases23
View on UniProt