Cortexin-2 (CTXN2)

About Cortexin-2

Cortexin-2 (CTXN2) is a protein from Homo sapiens identified by UniProt accession P0C2S0, 81 residues long. MolForge cross-references it against 0 known binders and 27 disease associations.

Target properties

Protein name	Cortexin-2
UniProt accession	P0C2S0
Gene	CTXN2
Organism	Homo sapiens
Length	81 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (27)

Diseases linked to this target (Open Targets).

hair colour measurement · score 0.23
skin pigmentation measurement · score 0.20
non-melanoma skin carcinoma · score 0.16
skin cancer · score 0.16
eye color · score 0.16
eye colour measurement · score 0.15
nose morphology measurement · score 0.13
skin pigmentation · score 0.13
urate measurement · score 0.06
refractive error measurement · score 0.05

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P0C2S0-F1	alphafold	PREDICTED	70.55	—

Amino-acid sequence (81 residues)

MSSTYCGNSS AKMSVNEVSA FSLTLEQKTG FAFVGILCIF LGLLIIRCFK ILLDPYSSMP SSTWEDEVEE FDKGTFEYAL A

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards