About Olfactory receptor 4E1
Olfactory receptor 4E1 (OR4E1) is a protein
from Homo sapiens identified by UniProt accession
P0C645, 315 residues long.
MolForge cross-references it against 0 known binders and
8 disease associations.
Target properties
| Protein name | Olfactory receptor 4E1 |
|---|
| UniProt accession | P0C645 |
|---|
| Gene | OR4E1 |
|---|
| Organism | Homo sapiens |
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| Length | 315 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (8)
Diseases linked to this target (Open Targets).
- monocyte count · score 0.13
- age at onset · score 0.12
- Myopia · score 0.12
- DNA methylation · score 0.04
- sleep measurement · score 0.03
- adolescent idiopathic scoliosis · score 0.02
- lung disease · score 0.00
- diabetes mellitus · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P0C645-F1 | alphafold | PREDICTED | 87.05 | — |
Amino-acid sequence (315 residues)
MEEAILLNQT SLVTYFRLRG LSVNHKARIA MFSMFLIFYV LTLIGNVLIV ITIIYDHRLH TPMYFFLSNL SFIDVCHSTV TVPKMLRDVW SEEKLISFDA CVTQMFFLHL FACTEIFLLT VMAYDRYVAI CKPLQYMIVM NWKVCVLLAV ALWTGGTIHS IALTSLTIKL PYCGPDEIDN FFCDVPQVIK LACIDTHVIE ILIVSNSGLI SVVCFVVLVV SYAVILVSLR QQISKGKRKA LSTCAAHLTV VTLFLGHCIF IYSRPSTSLP EDKVVSVFFT AVTPLLNPII YTLRNEEMKS ALNKLVGRKE RKEEK
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