About Protein BNIP5
Protein BNIP5 (BNIP5) is a protein
from Homo sapiens identified by UniProt accession
P0C671, 652 residues long.
MolForge cross-references it against 0 known binders and
18 disease associations.
Target properties
| Protein name | Protein BNIP5 |
|---|
| UniProt accession | P0C671 |
|---|
| Gene | BNIP5 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 652 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (18)
Diseases linked to this target (Open Targets).
- Familial prostate cancer · score 0.11
- prostate carcinoma · score 0.11
- prostate cancer · score 0.11
- Barrett's esophagus · score 0.06
- esophageal adenocarcinoma · score 0.05
- neuronal ceroid lipofuscinosis 1 · score 0.04
- non-small cell lung carcinoma · score 0.03
- leukocyte count · score 0.02
- Crohn's disease · score 0.02
- systemic lupus erythematosus · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P0C671-F1 | alphafold | PREDICTED | 47.52 | — |
Amino-acid sequence (652 residues)
MENPRCPRRP LAEKKARSLD RPQAPGKGSE SWDCHWLSLP TAPSRKALHW TTSDWARHSD SPAPSAEAHC TTAAAPTPEE TGDFLPSEQR PSQDTKKGWL KTMLNFFVRT GPEEPREKAS RRPRGKEGIS QHPEPLEAAG EPALRKKAHH DKKPSRKKQG HKKHAAEVTK AAQDQEARGR EEGLSKAAAA LRSGEADLGP ARRGGEDSDH QSFLIKVDGT GALDVSPHAT GHQQEEELKK PDQDAIIQMI VELLKRVGDQ WEEEQSLASQ LGVALPNPAP AVRKKSQEKK TSLKRTSKTN PKKHGSEEAK RGAADVSSPE AWPPKKSSFL PLCVSGHRPS ISSSYGLEEP KVQEAPSTEA GAPGPSVLPT PSESQEPGEE LPLDRASEYK EFIQKIISML QDAEEQQGEE QPQVQQEEVG VENPAPHCRR KSQEKRSSFR RAFYHKKHTS KEPRRAGAAG AASPEARRPK RPSFLPLCVG GHRPSTSSSL DPEDLECREP LPAEGEPVVI SEAPSQARGH TPEGAPQLSG ACESKEIIIQ KLVALLQEVD GQLGQQIRRH PSFKRFFYEF SDSSLSKLVA TLRSQVAHSS KLDRNRARRL YQFDVSLANK FAGSNSHAMC ILMGLRDHYN CTQFPYREDQ PNITSPKVES PD
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