About Tetraspanin-19
Tetraspanin-19 (TSPAN19) is a protein
from Homo sapiens identified by UniProt accession
P0C672, 248 residues long.
MolForge cross-references it against 0 known binders and
10 disease associations.
Target properties
| Protein name | Tetraspanin-19 |
|---|
| UniProt accession | P0C672 |
|---|
| Gene | TSPAN19 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 248 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (10)
Diseases linked to this target (Open Targets).
- optic disc size measurement · score 0.18
- vital capacity · score 0.11
- unipolar depression · score 0.10
- tendinitis · score 0.08
- PR interval · score 0.07
- body height · score 0.06
- papillary thyroid carcinoma · score 0.02
- neoplasm · score 0.00
- cancer · score 0.00
- mastitis · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P0C672-F1 | alphafold | PREDICTED | 90.79 | — |
Amino-acid sequence (248 residues)
MLRNNKTIII KYFLNLINGA FLVLGLLFMG FGAWLLLDRN NFLTAFDENN HFIVPISQIL IGMGSSTVLF CLLGYIGIHN EIRWLLIVYA VLITWTFAVQ VVLSAFIITK KEEVQQLWHD KIDFVISEYG SKDKPEDITK WTILNALQKT LQCCGQHNYT DWIKNKNKEN SGQVPCSCTK STLRKWFCDE PLNATYLEGC ENKISAWYNV NVLTLIGINF GLLTSEVFQV SLTVCFFKNI KNIIHAEM
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