Keratin-associated protein 2-3 (KRTAP2-3)

About Keratin-associated protein 2-3

Keratin-associated protein 2-3 (KRTAP2-3) is a protein from Homo sapiens identified by UniProt accession P0C7H8, 128 residues long. MolForge cross-references it against 0 known binders and 5 disease associations.

Target properties

Protein name	Keratin-associated protein 2-3
UniProt accession	P0C7H8
Gene	KRTAP2-3
Organism	Homo sapiens
Length	128 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (5)

Diseases linked to this target (Open Targets).

hair shape measurement · score 0.13
cystic fibrosis · score 0.03
Adams-Oliver syndrome · score 0.01
neoplasm · score 0.00
cancer · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P0C7H8-F1	alphafold	PREDICTED	32.89	—

Amino-acid sequence (128 residues)

MTGSCCGSTL SSLSYGGGCC QPCCCRDPCC CRPVTCQTTV CRPVTCVPRC TRPICEPCRR PVCCDPCSLQ EGCCRPITCC PSSCTAVVCR PCCWATTCCQ PVSVQSPCCR PPCGQPTPCS TTCRTSSC

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards