Rhox homeobox family member 2B (RHOXF2B)

About Rhox homeobox family member 2B

Rhox homeobox family member 2B (RHOXF2B) is a protein from Homo sapiens identified by UniProt accession P0C7M4, 288 residues long. MolForge cross-references it against 0 known binders and 6 disease associations.

Target properties

Protein name	Rhox homeobox family member 2B
UniProt accession	P0C7M4
Gene	RHOXF2B
Organism	Homo sapiens
Length	288 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (6)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.37
mental or behavioural disorder · score 0.02
alcohol-related disorders · score 0.02
chronic myelogenous leukemia · score 0.01
azoospermia · score 0.00
Azoospermia · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P0C7M4-F1	alphafold	PREDICTED	62.17	—

Amino-acid sequence (288 residues)

MEPPDQCSQY MTSLLSPAVD DEKELQDMNA MVLSLTEEVK EEEEDAQPEP EQGTAAGEKL KSAGAQGGEE KDGGGEEKDG GGAGVPGHLW EGNLEGTSGS DGNVEDSDQS EKEPGQQYSR PQGAVGGLEP GNAQQPNVHA FTPLQLQELE CIFQREQFPS EFLRRRLARS MNVTELAVQI WFENRRAKWR RHQRALMARN MLPFMAVGQP VMVTAAEAIT APLFISGMRD DYFWDHSHSS SLCFPMPPFP PPSLPLPLML LPPMPPAGQA EFGPFPFVIV PSFTFPNV

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards