IQ domain-containing protein F3 (IQCF3)

About IQ domain-containing protein F3

IQ domain-containing protein F3 (IQCF3) is a protein from Homo sapiens identified by UniProt accession P0C7M6, 154 residues long. MolForge cross-references it against 0 known binders and 2 disease associations.

Target properties

Protein name	IQ domain-containing protein F3
UniProt accession	P0C7M6
Gene	IQCF3
Organism	Homo sapiens
Length	154 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (2)

Diseases linked to this target (Open Targets).

sporadic amyotrophic lateral sclerosis · score 0.09
heel bone mineral density · score 0.02

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P0C7M6-F1	alphafold	PREDICTED	83.74	—

Amino-acid sequence (154 residues)

MGSKCCKGGP DEDAVERQRR QKLLLAQLHH RKRVKAAGQI QAWWRGVLVR RTLLVAALRA WMIQCWWRTL VQRRIRQRRQ ALLRVYVIQE QATVKLQSCI RMWQCRQCYR QMCNALCLFQ VPESSLAFQT DGFLQVQYAI PSKQPEFHIE ILSI

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards