About Protein ELFN1
Protein ELFN1 (ELFN1) is a protein
from Homo sapiens identified by UniProt accession
P0C7U0, 828 residues long.
MolForge cross-references it against 0 known binders and
147 disease associations.
Target properties
| Protein name | Protein ELFN1 |
|---|
| UniProt accession | P0C7U0 |
|---|
| Gene | ELFN1 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 828 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (147)
Diseases linked to this target (Open Targets).
- smoking status measurement · score 0.34
- smoking behavior · score 0.34
- systolic blood pressure · score 0.33
- smoking initiation · score 0.31
- attention deficit hyperactivity disorder · score 0.29
- mathematical ability · score 0.28
- antisocial behaviour measurement · score 0.27
- substance abuse · score 0.27
- gastroesophageal reflux disease · score 0.23
- blood protein measurement · score 0.22
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P0C7U0-F1 | alphafold | PREDICTED | 61.80 | — |
Amino-acid sequence (828 residues)
MAGRGWGALW VCVAAATLLH AGGLARADCW LIEGDKGFVW LAICSQNQPP YEAIPQQINS TIVDLRLNEN RIRSVQYASL SRFGNLTYLN LTKNEIGYIE DGAFSGQFNL QVLQLGYNRL RNLTEGMLRG LGKLEYLYLQ ANLIEVVMAS SFWECPNIVN IDLSMNRIQQ LNSGTFAGLA KLSVCELYSN PFYCSCELLG FLRWLAAFTN ATQTYDRMQC ESPPVYSGYY LLGQGRRGHR SILSKLQSVC TEDSYAAEVV GPPRPASGRS QPGRSPPPPP PPEPSDMPCA DDECFSGDGT TPLVALPTLA TQAEARPLIK VKQLTQNSAT ITVQLPSPFH RMYTLEHFNN SKASTVSRLT KAQEEIRLTN LFTLTNYTYC VVSTSAGLRH NHTCLTICLP RLPSPPGPVP SPSTATHYIM TILGCLFGMV LVLGAVYYCL RRRRRQEEKH KKAASAAAAG SLKKTIIELK YGPELEAPGL APLSQGPLLG PEAVTRIPYL PAAGEVEQYK LVESADTPKA SKGSYMEVRT GDPPERRDCE LGRPGPDSQS SVAEISTIAK EVDKVNQIIN NCIDALKSES TSFQGVKSGP VSVAEPPLVL LSEPLAAKHG FLAPGYKDAF GHSLQRHHSV EAAGPPRAST SSSGSVRSPR AFRAEAVGVH KAAAAEAKYI EKGSPAADAI LTVTPAAAVL RAEAEKGRQY GEHRHSYPGS HPAEPPAPPG PPPPPPHEGL GRKASILEPL TRPRPRDLAY SQLSPQYHSL SYSSSPEYTC RASQSIWERF RLSRRRHKEE EEFMAAGHAL RKKVQFAKDE DLHDILDYWK GVSAQHKS
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