Coiled-coil domain-containing protein 172 (CCDC172)

About Coiled-coil domain-containing protein 172

Coiled-coil domain-containing protein 172 (CCDC172) is a protein from Homo sapiens identified by UniProt accession P0C7W6, 258 residues long. MolForge cross-references it against 0 known binders and 6 disease associations.

Target properties

Protein name	Coiled-coil domain-containing protein 172
UniProt accession	P0C7W6
Gene	CCDC172
Organism	Homo sapiens
Length	258 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (6)

Diseases linked to this target (Open Targets).

Meckel syndrome · score 0.11
diet measurement · score 0.05
risk-taking behaviour · score 0.04
IGF-1 measurement · score 0.03
insulin like growth factor measurement · score 0.03
carcinoma of liver and intrahepatic biliary tract · score 0.01

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P0C7W6-F1	alphafold	PREDICTED	88.60	—

Amino-acid sequence (258 residues)

MSLESLFQHI IFTEHQAEES RRLMREVRSE ITRCREKIKK ATEELNEEKI KLESKVQQFF EKSFFLQLLK AHENALEKQY SEITNHRNML LQTFEAIKKQ MIEEEDKFIK EITDFNNDYE ITKKRELLMK ENVKIEISDL ENQANMLKSE MKSMEHDSSQ LNELQKQKSE LIQELFTLQR KLKVFEDEEN ESICTTKYLE AEKIKISEKP QNDTECLRLK KELELYKEDD MESVYEALQT EIEFLELTLA QKDLQESK

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards