About Zinc finger protein 688
Zinc finger protein 688 (ZNF688) is a protein
from Homo sapiens identified by UniProt accession
P0C7X2, 276 residues long.
MolForge cross-references it against 0 known binders and
8 disease associations.
Target properties
| Protein name | Zinc finger protein 688 |
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| UniProt accession | P0C7X2 |
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| Gene | ZNF688 |
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| Organism | Homo sapiens |
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| Length | 276 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (8)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.46
- sex hormone-binding globulin measurement · score 0.04
- erythrocyte count · score 0.03
- sarcoidosis · score 0.00
- carotid atherosclerosis · score 0.00
- Systemic lupus erythematosus · score 0.00
- fibrosis · score 0.00
- microphthalmia with limb anomalies · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P0C7X2-F1 | alphafold | PREDICTED | 59.02 | — |
Amino-acid sequence (276 residues)
MAPPPAPLLA PRPGETRPGC RKPGTVSFAD VAVYFSPEEW GCLRPAQRAL YRDVMQETYG HLGALGFPGP KPALISWMEQ ESEAWSPAAQ DPEKGERLGG ARRGDVPNRK EEEPEEVPRA KGPRKAPVKE SPEVLVERNP DPAISVAPAR AQPPKNAAWD PTTGAQPPAP IPSMDAQAGQ RRHVCTDCGR RFTYPSLLVS HRRMHSGERP FPCPECGMRF KRKFAVEAHQ WIHRSCSGGR RGRRPGIRAV PRAPVRGDRD PPVLFRHYPD IFEECG
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