About Phosphoinositide-interacting protein
Phosphoinositide-interacting protein (PIRT) is a protein
from Homo sapiens identified by UniProt accession
P0C851, 137 residues long.
MolForge cross-references it against 0 known binders and
21 disease associations.
Target properties
| Protein name | Phosphoinositide-interacting protein |
|---|
| UniProt accession | P0C851 |
|---|
| Gene | PIRT |
|---|
| Organism | Homo sapiens |
|---|
| Length | 137 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (21)
Diseases linked to this target (Open Targets).
- intracerebral hemorrhage · score 0.19
- arterial stiffness measurement · score 0.06
- familial episodic pain syndrome with predominantly lower limb involvement · score 0.03
- Undifferentiated Pancreatic Carcinoma · score 0.03
- colorectal cancer · score 0.02
- central nervous system cancer · score 0.02
- ependymoma · score 0.02
- neoplasm · score 0.01
- irritable bowel syndrome · score 0.01
- neuropathic pain · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P0C851-F1 | alphafold | PREDICTED | 63.97 | — |
Amino-acid sequence (137 residues)
MTMETLPKVL EVDEKSPEAK DLLPSQTASS LCISSRSESV WTTTPRSNWE IYRKPIVIMS VGGAILLFGV VITCLAYTLK LSDKSLSILK MVGPGFLSLG LMMLVCGLVW VPIIKKKQKH RQKSNFLRSL KSFFLTR
Explore Phosphoinositide-interacting protein with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets