About Complement C1q and tumor necrosis factor-related protein 9A
Complement C1q and tumor necrosis factor-related protein 9A (C1QTNF9) is a protein
from Homo sapiens identified by UniProt accession
P0C862, 333 residues long.
MolForge cross-references it against 0 known binders and
170 disease associations.
Target properties
| Protein name | Complement C1q and tumor necrosis factor-related protein 9A |
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| UniProt accession | P0C862 |
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| Gene | C1QTNF9 |
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| Organism | Homo sapiens |
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| Length | 333 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (170)
Diseases linked to this target (Open Targets).
- bone density · score 0.33
- urate measurement · score 0.32
- serum gamma-glutamyl transferase measurement · score 0.28
- platelet crit · score 0.12
- platelet count · score 0.12
- mean corpuscular volume · score 0.12
- reticulocyte measurement · score 0.12
- hypothyroidism · score 0.12
- type 2 diabetes mellitus · score 0.11
- myocardial infarction · score 0.11
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P0C862-F1 | alphafold | PREDICTED | 63.72 | — |
Amino-acid sequence (333 residues)
MRIWWLLLAI EICTGNINSQ DTCRQGHPGI PGNPGHNGLP GRDGRDGAKG DKGDAGEPGR PGSPGKDGTS GEKGERGADG KVEAKGIKGD QGSRGSPGKH GPKGLAGPMG EKGLRGETGP QGQKGNKGDV GPTGPEGPRG NIGPLGPTGL PGPMGPIGKP GPKGEAGPTG PQGEPGVRGI RGWKGDRGEK GKIGETLVLP KSAFTVGLTV LSKFPSSDMP IKFDKILYNE FNHYDTAAGK FTCHIAGVYY FTYHITVFSR NVQVSLVKNG VKILHTKDAY MSSEDQASGG IVLQLKLGDE VWLQVTGGER FNGLFADEDD DTTFTGFLLF SSP
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