About Protein FAM228B
Protein FAM228B (FAM228B) is a protein
from Homo sapiens identified by UniProt accession
P0C875, 324 residues long.
MolForge cross-references it against 0 known binders and
29 disease associations.
Target properties
| Protein name | Protein FAM228B |
|---|
| UniProt accession | P0C875 |
|---|
| Gene | FAM228B |
|---|
| Organism | Homo sapiens |
|---|
| Length | 324 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (29)
Diseases linked to this target (Open Targets).
- lifestyle measurement · score 0.19
- neutrophil count · score 0.18
- myeloid white cell count · score 0.15
- appendicular lean mass · score 0.12
- leukocyte count · score 0.12
- essential tremor · score 0.11
- granulocyte count · score 0.10
- reticulocyte measurement · score 0.10
- reticulocyte count · score 0.09
- sum of neutrophil and eosinophil counts · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P0C875-F1 | alphafold | PREDICTED | 67.86 | — |
Amino-acid sequence (324 residues)
MKNVDSDDLV TGTLPKLKSS KEWLEPKPLC FMEVLAKEDT EAAIQSILYK ENSVIKELDK YLQHHAFLNA RRKEMLYKRW VDCVADPLQK KIIEKVCSHK KIKKRRQGEL DGFLKHVNKK GNAFIEHYDP KEYDPFYMSK KDPNFLKVTI PPFHDPLKKA QYDKDNEKRT LLQCETGKIY SIKEFKEVEK VQLHSRFPQI SNSRHFITPN EWLKLPTRYI ESEFCRRRRL KVKVNFNDCS FDLKPLARAP YLLESQEEEK TVIYKNKGSS FLEREPLCYQ EGNNPSAKEA ISEGYFSSLS LSQEREEDQD GSPSPRLGLL KLEL
Explore Protein FAM228B with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets