Prostate and testis expressed protein 4 (PATE4)

About Prostate and testis expressed protein 4

Prostate and testis expressed protein 4 (PATE4) is a protein from Homo sapiens identified by UniProt accession P0C8F1, 98 residues long. MolForge cross-references it against 0 known binders and 25 disease associations.

Target properties

Protein name	Prostate and testis expressed protein 4
UniProt accession	P0C8F1
Gene	PATE4
Organism	Homo sapiens
Length	98 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (25)

Diseases linked to this target (Open Targets).

mean platelet volume · score 0.25
hemoglobin D disease · score 0.05
MODY · score 0.05
dominant beta-thalassemia · score 0.04
hemoglobin H disease · score 0.04
hemoglobin E disease · score 0.04
hemoglobin C-beta-thalassemia syndrome · score 0.04
attention deficit hyperactivity disorder · score 0.04
diabetes mellitus, permanent neonatal 4 · score 0.04
diabetes mellitus, transient neonatal, 3 · score 0.03

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P0C8F1-F1	alphafold	PREDICTED	91.13	—

Amino-acid sequence (98 residues)

MRKMNTLLLV SLSFLYLKEV MGLKCNTCIY TEGWKCMAGR GTCIAKENEL CSTTAYFRGD KHMYSTHMCK YKCREEESSK RGLLRVTLCC DRNFCNVF

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards