Polyadenylate-binding protein 4-like (PABPC4L)

About Polyadenylate-binding protein 4-like

Polyadenylate-binding protein 4-like (PABPC4L) is a protein from Homo sapiens identified by UniProt accession P0CB38, 370 residues long. MolForge cross-references it against 0 known binders and 29 disease associations.

Target properties

Protein name	Polyadenylate-binding protein 4-like
UniProt accession	P0CB38
Gene	PABPC4L
Organism	Homo sapiens
Length	370 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (29)

Diseases linked to this target (Open Targets).

body height · score 0.40
lean body mass · score 0.38
birth weight · score 0.29
FEV/FVC ratio · score 0.28
body height at birth · score 0.25
alcohol consumption measurement · score 0.23
wellbeing measurement · score 0.23
whole body water mass · score 0.21
base metabolic rate measurement · score 0.20
body weight · score 0.19

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P0CB38-F1	alphafold	PREDICTED	91.86	—

Amino-acid sequence (370 residues)

MNVAAKYRMA SLYVGDLHAD VTEDLLFRKF STVGPVLSIR ICRDQVTRRS LGYAYVNFLQ LADAQKALDT MNFDIIKGKS IRLMWSQRDA YLRRSGIGNV FIKNLDKSID NKTLYEHFSA FGKILSSKVM SDDQGSKGYA FVHFQNQSAA DRAIEEMNGK LLKGCKVFVG RFKNRKDREA ELRSKASEFT NVYIKNFGGD MDDERLKDVF SKYGKTLSVK VMTDSSGKSK GFGFVSFDSH EAAKKAVEEM NGRDINGQLI FVGRAQKKVE RQAELKQMFE QLKRERIRGC QGVKLYIKNL DDTIDDEKLR NEFSSFGSIS RVKVMQEEGQ SKGFGLICFS SPEDATKAMT EMNGRILGSK PLSIALAQRH

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards