Upstream-binding factor 1-like protein 1 (UBTFL1)

About Upstream-binding factor 1-like protein 1

Upstream-binding factor 1-like protein 1 (UBTFL1) is a protein from Homo sapiens identified by UniProt accession P0CB47, 393 residues long. MolForge cross-references it against 0 known binders and 10 disease associations.

Target properties

Protein name	Upstream-binding factor 1-like protein 1
UniProt accession	P0CB47
Gene	UBTFL1
Organism	Homo sapiens
Length	393 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (10)

Diseases linked to this target (Open Targets).

urinary metabolite measurement · score 0.17
lean body mass · score 0.05
serum metabolite measurement · score 0.04
hair colour measurement · score 0.03
self reported educational attainment · score 0.02
substance abuse · score 0.02
attention deficit hyperactivity disorder · score 0.02
antisocial behaviour measurement · score 0.02
gastric carcinoma · score 0.01
embryonal carcinoma · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P0CB47-F1	alphafold	PREDICTED	70.35	—

Amino-acid sequence (393 residues)

MALPRSQGHW SNKDILRLLE CMENNRPSDD NSTFSSTQSH MDWGKVAFKN FSGEMCRLKW LEISCNLRKF GTLKELVLEA KKCVKKMNKS QKYRNGPDFP KRPLTAYNRF FKESWPQYSQ MYPGMRSQEL TKILSKKYRE LPEQMKQKYI QDFRKEKQEF EEKLARFREE HPDLVQKAKK SSVSKRTQNK VQKKFQKNIE EVRSLPKTDR FFKKVKFHGE PQKPPMNGYH KFHQDSWSSK EMQHLSVRER MVEIGRRWQR IPQSQKDHFK SQAEELQKQY KVKLDLWLKT LSPENYAAYK ESTYAKGKNM AMTGGPDPRL KQADPQSSSA KGLQEGFGEG QGLQAAGTDS SQTIWVNCHV SMEPEENRKK DREKEESSNS SDCSSGEEIE VDV

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards