Endogenous Bornavirus-like nucleoprotein 1 (EBLN1)

About Endogenous Bornavirus-like nucleoprotein 1

Endogenous Bornavirus-like nucleoprotein 1 (EBLN1) is a protein from Homo sapiens identified by UniProt accession P0CF75, 366 residues long. MolForge cross-references it against 0 known binders and 21 disease associations.

Target properties

Protein name	Endogenous Bornavirus-like nucleoprotein 1
UniProt accession	P0CF75
Gene	EBLN1
Organism	Homo sapiens
Length	366 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (21)

Diseases linked to this target (Open Targets).

calcium measurement · score 0.44
monocyte percentage of leukocytes · score 0.33
lower urinary tract symptom · score 0.31
benign prostatic hyperplasia · score 0.31
lymphocyte:monocyte ratio · score 0.28
lymphocyte count · score 0.27
amyloid-beta measurement · score 0.27
myeloid white cell count · score 0.23
granulocyte percentage of myeloid white cells · score 0.19
subcutaneous adipose tissue measurement · score 0.16

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P0CF75-F1	alphafold	PREDICTED	84.42	—

Amino-acid sequence (366 residues)

MSRPRNNPQT SSPQDSTKDG SSFHYFQGRF ELSGKSRQYP ADALEPQPGI GDVKVIEKAT KSMLDPAQRS HFYLVTPSLV FLCFIFDGLH KALLSVGVSK RSNIVIGNEN KETGTLYASK FEDVLPTFTA LEMSSILRHC CDLIGIAAGS SDPICTNSLQ VQRQFKAMMI SIGRPLHSES ADLLISYNAG PAIDWINSRP WVGGLMFTFL FGEFESPACE LLDQVKVVAS KAQMMTYYTV RMFLDQCVDG STALPAVVLE IPVFEQKKPL AKKVLGDFFE FGGVLRHPVI GVLSPQMFPN LATAANYWAK RRNSTFSGFE ALDIIPGSTI TFPVLQMASA QKISRGSDMD PYTLNILRGY GISGFE

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards