About Protein FAM200B
Protein FAM200B (FAM200B) is a protein
from Homo sapiens identified by UniProt accession
P0CF97, 657 residues long.
MolForge cross-references it against 0 known binders and
21 disease associations.
Target properties
| Protein name | Protein FAM200B |
| UniProt accession | P0CF97 |
| Gene | FAM200B |
| Organism | Homo sapiens |
| Length | 657 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | UNCLASSIFIED |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (21)
Diseases linked to this target (Open Targets).
- urinary metabolite measurement · score 0.27
- mean corpuscular volume · score 0.22
- ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2 measurement · score 0.12
- mean reticulocyte volume · score 0.11
- Red cell distribution width · score 0.11
- erythrocyte count · score 0.11
- mean corpuscular hemoglobin concentration · score 0.11
- mean corpuscular hemoglobin · score 0.10
- risk-taking behaviour · score 0.10
- red blood cell density measurement · score 0.09
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
| AF-P0CF97-F1 | alphafold | PREDICTED | 80.71 | — |
Amino-acid sequence (657 residues)
MDHFFIKRKR NSEVKYTEAC SSSSVESGIV NSDNIEKNTD SNLQTSTSFE PHFKKKKVSA RRYNEDYLKY GFIKCEKPFE NDRPQCVICN NILANESLKP SKLKRHLETQ HAELIDKPLE YFQRKKKDIK LSTQFLSCST AVSEKALLSS YLVAYRVAKE KIANTAAEKI ILPACLDMVR TIFDDKSADK LKTIPNDNTV SLRICTIAEH LETMLITRLQ SGIDFAIQLD ESTDIGSCTT LLVYVRYAWQ DDFLEDFLCF LNLTSHLSGL DIFTELERRI VGQYKLNWKN CKGITSDGTA TMTGKHSRVI KKLLEVTNNG AVWNHCFIHR EGLASREIPQ NLMEVLKNAV KVVNFIKGSS LNSRLLETFC SEIGTNHTHL LYHTKIRWLS QGKILSRVYE LRNEIHFFLI EKKSHLASIF EDDTWVTKLA YLTDIFSILN ELSLKLQGKN SDVFQHVERI QGFRKTLLLW QVRLKSNRPS YYMFPRFLQH IEENIINENI LKEIKLEILL HLTSLSQTFN HFFPEEKFET LRENSWVKDP FAFRHPESII ELNLVPEEEN ELLQLSSSYT LKNDYETLSL SAFWMKVKED FPLLSRKSVL LLLPFTTTSL CELGFSILTQ LKTKERNGLN CAAVMRVALS SCVPDWNELM NRQAHPS
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