Chromosome transmission fidelity protein 8 homolog…

About Chromosome transmission fidelity protein 8 homolog

Chromosome transmission fidelity protein 8 homolog (CHTF8) is a protein from Homo sapiens identified by UniProt accession P0CG13, 121 residues long. MolForge cross-references it against 0 known binders and 26 disease associations.

Target properties

Protein name	Chromosome transmission fidelity protein 8 homolog
UniProt accession	P0CG13
Gene	CHTF8
Organism	Homo sapiens
Length	121 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (26)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.28
heel bone mineral density · score 0.21
body height · score 0.15
high density lipoprotein cholesterol measurement · score 0.14
cortical thickness · score 0.12
body mass index · score 0.10
neuroimaging measurement · score 0.08
brain measurement · score 0.08
non-melanoma skin carcinoma · score 0.07
skin cancer · score 0.07

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P0CG13-F1	alphafold	PREDICTED	86.51	—

Amino-acid sequence (121 residues)

MVQIVISSAR AGGLAEWVLM ELQGEIEARY STGLAGNLLG DLHYTTEGIP VLIVGHHILY GKIIHLEKPF AVLVKHTPGD QDCDELGRET GTRYLVTALI KDKILFKTRP KPIITSVPKK V

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards

Chromosome transmission fidelity protein 8 homolog (CHTF8)