About Zinc finger protein 853
Zinc finger protein 853 (ZNF853) is a protein
from Homo sapiens identified by UniProt accession
P0CG23, 659 residues long.
MolForge cross-references it against 0 known binders and
16 disease associations.
Target properties
| Protein name | Zinc finger protein 853 |
|---|
| UniProt accession | P0CG23 |
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| Gene | ZNF853 |
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| Organism | Homo sapiens |
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| Length | 659 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (16)
Diseases linked to this target (Open Targets).
- vital capacity · score 0.32
- neurodegenerative disease · score 0.24
- mean corpuscular hemoglobin concentration · score 0.17
- brain measurement · score 0.12
- body mass index · score 0.10
- blood phosphate measurement · score 0.08
- body fat percentage · score 0.07
- myeloid white cell count · score 0.04
- leukocyte count · score 0.03
- monocyte count · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P0CG23-F1 | alphafold | PREDICTED | 65.45 | — |
Amino-acid sequence (659 residues)
MLHQPTPGNR GLTARMEVGP ATETFVLELQ CLEDGGPGPD TLSGGSGGSE SQEEEEPQER NSSPQRPAVS APVGASEIAE ETRPGQRELQ LQQLEQQPEP QQQPQHEQLQ QPQPHLELQQ QPQQDGQQQL SQLQQEKHQS VHHQELKPEL QLMHQQQQLQ PQQVQEQQRL QQQQEQLQTQ QAQEQQVLQQ QEQLQQQVQE QQLLQQQQEQ LQQQQLLQQQ EQLQQQQFQQ QQEQLQQQQQ LLLLQQQGQL QQQLLQQQQA QLQQQLLEQQ QAQLQQQLLL QQQEQLQQQQ QQQLLQQQQE QLQQQQLQPP PLEPEEEEEV ELELMPVDLG SEQELEQQRQ ELERQQELER QQEQRQLQLK LQEELQQLEQ QLEQQQQQLE QQEVQLELTP VELGAQQQEV QLELTPVQPE LQLELVPAAG GGGAAVPGAP AAVVVAPPGY VVVQELMVLP AVAAPAVVAI PGPAGSAALT PARQRRRRRA RDRPTICGEC GKGFSRSTDL VRHQATHTGE RPHRCGECGK GFSQHSNLVT HQRIHTGEKP YACSYCAKRF SESSALVQHQ RTHTGERPYA CGDCGKRFSV SSNLLRHRRT HSGERPYVCE DCGERFRHKV QIRRHERQLH GAGRSRGLGL LRASRPAALG GPARAEQAAT ATAPADKAL
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