About Cryptic family protein 1B
Cryptic family protein 1B (CFC1B) is a protein
from Homo sapiens identified by UniProt accession
P0CG36, 223 residues long.
MolForge cross-references it against 0 known binders and
79 disease associations.
Target properties
| Protein name | Cryptic family protein 1B |
|---|
| UniProt accession | P0CG36 |
|---|
| Gene | CFC1B |
|---|
| Organism | Homo sapiens |
|---|
| Length | 223 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (79)
Diseases linked to this target (Open Targets).
- Heterotaxia · score 0.09
- visceral heterotaxy · score 0.08
- heterotaxy, visceral, 12, autosomal · score 0.08
- right atrial isomerism · score 0.08
- congenital heart defects, multiple types, 6 · score 0.07
- congenital heart disease · score 0.06
- heterotaxy, visceral, 5, autosomal · score 0.06
- tricuspid atresia · score 0.06
- scimitar syndrome · score 0.06
- heterotaxy, visceral, 9, autosomal, with male infertility · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P0CG36-F1 | alphafold | PREDICTED | 63.95 | — |
Amino-acid sequence (223 residues)
MTWRHHVRLL FTVSLALQII NLGNSYQREK HNGGREEVTK VATQKHRQSP LNWTSSHFGE VTGSAEGWGP EEPLPYSWAF GEGASARPRC CRNGGTCVLG SFCVCPAHFT GRYCEHDQRR SECGALEHGA WTLRACHLCR CIFGALHCLP LQTPDRCDPK DFLASHAHGP SAGGAPSLLL LLPCALLHRL LRPDAPAHPR SLVPSVLQRE RRPCGRPGLG HRL
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