About POTE ankyrin domain family member I
POTE ankyrin domain family member I (POTEI) is a protein
from Homo sapiens identified by UniProt accession
P0CG38, 1075 residues long.
MolForge cross-references it against 0 known binders and
5 disease associations.
Target properties
| Protein name | POTE ankyrin domain family member I |
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| UniProt accession | P0CG38 |
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| Gene | POTEI |
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| Organism | Homo sapiens |
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| Length | 1075 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (5)
Diseases linked to this target (Open Targets).
- neoplasm · score 0.00
- non-small cell lung carcinoma · score 0.00
- triple-negative breast cancer · score 0.00
- Waardenburg syndrome · score 0.00
- thromboangiitis obliterans · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P0CG38-F1 | alphafold | PREDICTED | 70.70 | — |
Amino-acid sequence (1075 residues)
MVAEVDSMPA ASSVKKPFVL RSKMGKWCRH CFPCCRGSGK SNVGTSGDQD DSTMKTLRSK MGKWCCHCFP CCRGSGKSNV GTSGDHDDSA MKTLRSKMGK WCCHCFPCCR GSGKSNVGAW GDYDDSAFVE PRYHVRREDL DKLHRAAWWG KVARKDLIVM LRDTDVNKQD KQKRTALHLA SANGNSGVVK LLLDRRCQLN VLDNKKRTAL TKAVQCQEDE CALMLLEHGT DPNIPDEYGN TTLHYAIYNE DKLMAKALLL YGADIESKNK HGLTPLLLGV HEQKQQVVKF LIKKKANLNA LDRYGRTALI LAVCCGSASI VSLLLEQNID VSSQDLSGQT AREYAVSSHH HVICQLLSDY KEKQMLKISS ENSNPEQDLK LTSEEESQRF KGSENSQPEK MSQEPEINKD GDREVEEEMK KHESNNVGLL ENLSNGVTAG NGDDGLIPQR KSRTPENQQF PDNESEEYHR ICELVSDYKE KQMPKYSSEN SNPEQDLKLT SEEESQRLKG SENGQPEKRS QEPEINKDGD RELENFMAIE EMKKHGSTHV GFPENLTNGA TAGNGDDGLI PPRKSRTPES QQFPDTENEE YHSDEQNDTQ KQFCEEQNTG ILHDEILIHE EKQIEVVEKM NSELSLSCKK EKDFLHENST LREEIAMLRL ELDTMKHQSQ LRKKKYLEDI ESVKKKNDNL LKALQLNELT MDDDTAVLVI DNGSGMCKAG FAGDDAPRAV FPSIVGRPRQ QGMMGGMHQK ESYVGKEAQS KRGILTLKYP MEHGIITNWD DMEKIWHHTF YNELRVAPEE HPILLTEAPL NPKANREKMT QIMFETFNTP AMYVAIQAML SLYTSGRTTG IVMDSGDGVT HTVPIYDGNA LPHATLRLDL AGRELTDYLM KILTERGYRF TTMAEREIVR DIKEKLCYVA LDFEQEMAMA ASSSSLEKSY ELPDGQVITI GNEWFRCPEA LFQPCFLGME SCGIHETTFN SIMKSDVDIR KDLYTNTVLS GGTTMYPGMA HRMQKEIAAL APSMLKIRII APPKRKYSVW VGGSILASLS TFQQMWISKQ EYDESGPSIV HRKCF
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