Tripartite motif-containing protein 49C (TRIM49C)

About Tripartite motif-containing protein 49C

Tripartite motif-containing protein 49C (TRIM49C) is a protein from Homo sapiens identified by UniProt accession P0CI26, 452 residues long. MolForge cross-references it against 0 known binders and 5 disease associations.

Target properties

Protein name	Tripartite motif-containing protein 49C
UniProt accession	P0CI26
Gene	TRIM49C
Organism	Homo sapiens
Length	452 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (5)

Diseases linked to this target (Open Targets).

basophil count · score 0.17
gastric adenocarcinoma · score 0.14
hair colour measurement · score 0.03
hemolytic anemia · score 0.03
urinary metabolite measurement · score 0.02

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P0CI26-F1	alphafold	PREDICTED	84.48	—

Amino-acid sequence (452 residues)

MNSGILQVFQ GELICPLCMN YFIDPVTIDC GHSFCRPCFY LNWQDIPFLV QCSECTKSTE QINLKTNIHL KKMASLARKV SLWLFLSSEE QMCGTHRETK KIFCEVDRSL LCLLCSSSQE HRYHRHRPIE WAAEEHREKL LQKMQSLWEK ACENHRNLNV ETTRTRCWKD YVNLRLEAIR AEYQKMPAFH HEEEKHNLEM LKKKGKEIFH RLHLSKAKMA HRMEILRGMY EELNEMCHKP DVELLQAFGD ILHRSESVLL HMPQPLNPEL SAGPITGLRD RLNQFRVHIT LHHEEANSDI FLYEILRSMC IGCDHQDVPY FTATPRSFLA WGVQTFTSGK YYWEVHVGDS WNWAFGVCNM YRKEKNQNEK IDGKEGLFLL GCIKNDIQCS LFTTSPLMLQ YIPKPTSRVG LFLDCEAKTV SFVDVNQSSL IYTIPNCSFS PPLRPIFCCI HF

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards