About Zinc finger protein 888
Zinc finger protein 888 (ZNF888) is a protein
from Homo sapiens identified by UniProt accession
P0CJ79, 718 residues long.
MolForge cross-references it against 0 known binders and
11 disease associations.
Target properties
| Protein name | Zinc finger protein 888 |
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| UniProt accession | P0CJ79 |
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| Gene | ZNF888 |
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| Organism | Homo sapiens |
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| Length | 718 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (11)
Diseases linked to this target (Open Targets).
- Red cell distribution width · score 0.13
- blood phosphate measurement · score 0.13
- cystatin C measurement · score 0.11
- mean reticulocyte volume · score 0.11
- urate measurement · score 0.04
- monocyte count · score 0.04
- eosinophil count · score 0.03
- mean corpuscular volume · score 0.03
- platelet crit · score 0.03
- platelet count · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P0CJ79-F1 | alphafold | PREDICTED | 69.85 | — |
Amino-acid sequence (718 residues)
MALPQGLLTF RDVAIEFSQE EWKCLDPAQR TLYRDVMLEN YRNLVSLDIS SKCMMEFSSI GKGNTEVIHT GTLQRLASHH IGECCFQEIE KDIHDFVFQW QEDETNGHEA PMTEIKELTG STDQYDQRHA GNKPIKYQLG SSFHSHLPEL HIFQPEGKIG NQLEKSINNA SSVSTSQRIS CRPKTHISNN YGNNFFHSSL LTQKQDVHRK EKSFQFNESG KSFNCSSLFK KHQIIHLGEK QYKCDVCGKD FNQKRYLAHH RRCHTGEKPY MCNKCGKVFN KKAYLARHYR RHTGEKPYKC NECGKTFSDK SALLVHKTIH TGEKPYKCNE CGKVFNQQSN LARHHRVHTG EKPYQCKECD KVFSRKSYLE RHRRIHTGEK PYKCKVCDKA FRHDSHLAQH IVIHTREKPY KCNECGKTFG ENSALLVHKT IHTGEKPYKC NECGKVFNQQ SNLARHHRLH TGEKPYKCKE CDKVFSRKSH LERHRRIHTG EKPYKCKVCD KAFRRDSHLA QHTVIHTGEK PYKCNECGKT FVQNSSLVMH KVIHTGEKRY KCNECGKSFN HKSSLAYHHR LHTGEKPYKC NECGKVFRTQ SQLACHHRLH TGEKPYKCEE CDKVFNIKSH LEIHRRVHTG EKPYKCRVCD KAFGRDSYLA QHQRVHTGEK PYKCKVCDKA FKCYSHLAQH TRIHTGEKPF KCSECGKAFR AQSTLIHHQA IHGVGKLD
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