Testis-specific Y-encoded protein 4 (TSPY4)

About Testis-specific Y-encoded protein 4

Testis-specific Y-encoded protein 4 (TSPY4) is a protein from Homo sapiens identified by UniProt accession P0CV99, 314 residues long. MolForge cross-references it against 0 known binders and 3 disease associations.

Target properties

Protein name	Testis-specific Y-encoded protein 4
UniProt accession	P0CV99
Gene	TSPY4
Organism	Homo sapiens
Length	314 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (3)

Diseases linked to this target (Open Targets).

cryptorchidism · score 0.00
Infertility · score 0.00
infectious disease · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P0CV99-F1	alphafold	PREDICTED	71.68	—

Amino-acid sequence (314 residues)

MRPEGSLTYR VPERLRQGFC GVGRAAQALV CASAKEGTAF RMEAVQEGAA GVESEQAALG EEAVLLLDDI MAEVEVVAEV EVVAEEEGLV ERREEAQRAQ QAVPGPGPMT PESALEELLA VQVELEPVNA QARKAFSRQR EKMERRRKPH LDRRGAVIQS VPGFWANVIA NHPQMSALIT DEDEDMLSYM VSLEVEEEKH PVHLCKIMLF FRSNPYFQNK VITKEYLVNI TEYRASHSTP IEWYPDYEVE AYRRRHHNSS LNFFNWFSDH NFAGSNKIAE ILCKDLWRNP LQYYKRMKPP EEGTETSGDS QLLS

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards