Testis-specific Y-encoded protein 10 (TSPY10)

Homo sapiens — UniProt P0CW01

Gene: TSPY10Homo sapiensSwissProt reviewed

About Testis-specific Y-encoded protein 10

Testis-specific Y-encoded protein 10 (TSPY10) is a protein from Homo sapiens identified by UniProt accession P0CW01, 308 residues long. MolForge cross-references it against 0 known binders and 43 disease associations.

Target properties

Protein nameTestis-specific Y-encoded protein 10
UniProt accessionP0CW01
GeneTSPY10
OrganismHomo sapiens
Length308 residues
Molecular weight—
EC numbers—
Target classUNCLASSIFIED
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (43)

Diseases linked to this target (Open Targets).

  • hepatocellular carcinoma · score 0.09
  • neoplasm · score 0.05
  • cancer · score 0.04
  • gonadoblastoma · score 0.02
  • disorder of sexual differentiation · score 0.02
  • dysgerminoma · score 0.01
  • adenocarcinoma · score 0.01
  • male infertility · score 0.01
  • melanoma · score 0.01
  • Infertility · score 0.01

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-P0CW01-F1alphafoldPREDICTED74.40—

Amino-acid sequence (308 residues)

MRPEGSLTYR VPERLRQGFC GVGRAAQALV CASAKEGTAF RMEAVQEGAA GVESEQAALG EEAVLLLDDI MAEVEVVAEE EGLVERREEA QRAQQAVPGP GPMTPESALE ELLAVQVELE PVNAQARKAF SRQREKMERR RKPHLDRRGA VIQSVPGFWA NVIANHPQMS ALITDEDEDM LSYMVSLEVE EEKHPVHLCK IMLFFRSNPY FQNKVITKEY LVNITEYRAS HSTPIEWYPD YEVEAYRRRH HNSSLNFFNW FSDHNFAGSN KIAEILCKDL WRNPLQYYKR MKPPEEGTET SGDSQLLS

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Quick facts

UniProtP0CW01
GeneTSPY10
OrganismHomo sapiens
Length308
Binders0
Diseases43
View on UniProt