About Testis-specific Y-encoded protein 10
Testis-specific Y-encoded protein 10 (TSPY10) is a protein
from Homo sapiens identified by UniProt accession
P0CW01, 308 residues long.
MolForge cross-references it against 0 known binders and
43 disease associations.
Target properties
| Protein name | Testis-specific Y-encoded protein 10 |
| UniProt accession | P0CW01 |
| Gene | TSPY10 |
| Organism | Homo sapiens |
| Length | 308 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | UNCLASSIFIED |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (43)
Diseases linked to this target (Open Targets).
- hepatocellular carcinoma · score 0.09
- neoplasm · score 0.05
- cancer · score 0.04
- gonadoblastoma · score 0.02
- disorder of sexual differentiation · score 0.02
- dysgerminoma · score 0.01
- adenocarcinoma · score 0.01
- male infertility · score 0.01
- melanoma · score 0.01
- Infertility · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
| AF-P0CW01-F1 | alphafold | PREDICTED | 74.40 | — |
Amino-acid sequence (308 residues)
MRPEGSLTYR VPERLRQGFC GVGRAAQALV CASAKEGTAF RMEAVQEGAA GVESEQAALG EEAVLLLDDI MAEVEVVAEE EGLVERREEA QRAQQAVPGP GPMTPESALE ELLAVQVELE PVNAQARKAF SRQREKMERR RKPHLDRRGA VIQSVPGFWA NVIANHPQMS ALITDEDEDM LSYMVSLEVE EEKHPVHLCK IMLFFRSNPY FQNKVITKEY LVNITEYRAS HSTPIEWYPD YEVEAYRRRH HNSSLNFFNW FSDHNFAGSN KIAEILCKDL WRNPLQYYKR MKPPEEGTET SGDSQLLS
Explore Testis-specific Y-encoded protein 10 with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets